Anti-Dendrin/DDN antibody (1-50) (STJ506041)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide taken within amino acid region 1-50 on human Dendrin.
General Information
| Short Description | Rabbit polyclonal antibody anti-Dendrin/DDN (1-50) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5-1.5 ยตg/ยตl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:500ELISA: 1:50, 000IP: 1:200 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | DDN |
| Gene ID | 23109 |
| Uniprot ID | DEND_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid region 1-50 on human Dendrin. |
| Immunogen Region | 1-50 |
Additional Info
| Tissue Specificity | Specifically expressed in brain and kidney. Expressed in kidney glomerular capillary loops (at protein level). |
| Function | Promotes apoptosis of kidney glomerular podocytes. Podocytes are highly specialized cells essential to the ultrafiltration of blood, resulting in the extraction of urine and the retention of protein. |
| Protein Name | Dendrin |
| Cellular Localisation | Cell ProjectionDendritic Spine MembranePeripheral Membrane ProteinCytoplasmEndoplasmic Reticulum MembraneCytoplasmic SidePerikaryonNucleusEnriched At The Cytoplasmic Insertion Of The Slit Diaphragm Into The Foot Process Of Podocytes And Associated With Polyribosomes In Dendrites |
| Alternative Antibody Names | Anti-Dendrin antibodyAnti-DDN antibodyAnti-KIAA0749 antibody |
Information sourced from Uniprot.org