| Host: |
Rabbit |
| Applications: |
ELISA/IP/WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Dendrin/DDN (1-50) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Biotin |
| Isotype: |
IgG |
| Purification: |
Affinity Purified |
| Concentration: |
0.5-1.5 µg/µl |
| Dilution Range: |
WB: 1:500ELISA: 1:50, 000IP: 1:200 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
DDN |
| Gene ID: |
23109 |
| Uniprot ID: |
DEND_HUMAN |
| Immunogen Region: |
1-50 |
| Immunogen: |
Synthetic peptide taken within amino acid region 1-50 on human Dendrin. |
| Tissue Specificity | Specifically expressed in brain and kidney. Expressed in kidney glomerular capillary loops (at protein level). |
| Function | Promotes apoptosis of kidney glomerular podocytes. Podocytes are highly specialized cells essential to the ultrafiltration of blood, resulting in the extraction of urine and the retention of protein. |
| Protein Name | Dendrin |
| Cellular Localisation | Cell ProjectionDendritic Spine MembranePeripheral Membrane ProteinCytoplasmEndoplasmic Reticulum MembraneCytoplasmic SidePerikaryonNucleusEnriched At The Cytoplasmic Insertion Of The Slit Diaphragm Into The Foot Process Of Podocytes And Associated With Polyribosomes In Dendrites |
| Alternative Antibody Names | Anti-Dendrin antibodyAnti-DDN antibodyAnti-KIAA0749 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
