Anti-DEFB1 antibody (N-Term) (STJA0005717)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide corresponding to amino acids from the N-terminal region of human beta Defensin protein
General Information
| Short Description | Rabbit polyclonal anti-Beta-Defensin (N-Term) for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Antigen Affinity Purified |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | PBS + 0.02% NaN3 |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DEFB1 |
| Gene ID | 1672 |
| Uniprot ID | DEFB1_HUMAN |
| Immunogen | Synthetic peptide corresponding to amino acids from the N-terminal region of human beta Defensin protein |
| Immunogen Region | N-Term |
| Specificity | Reacts with the N-terminal region of human beta Defensin protein |
Additional Info
| Function | Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. |
| Protein Name | Beta-Defensin 1Bd-1Hbd-1Defensin - Beta 1 |
| Database Links | Reactome: R-HSA-1461957Reactome: R-HSA-1461973 |
| Cellular Localisation | SecretedMembraneAssociates With Tumor Cell Membrane-Derived Microvesicles |
| Alternative Antibody Names | Anti-Beta-Defensin 1 antibodyAnti-Bd-1 antibodyAnti-Hbd-1 antibodyAnti-Defensin - Beta 1 antibodyAnti-DEFB1 antibodyAnti-BD1 antibodyAnti-HBD1 antibody |
Information sourced from Uniprot.org