Anti-DEDD2 antibody (226-276) (STJA0006449)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human DEDD2 AA range: 226-276
General Information
| Short Description | Rabbit polyclonal anti-DNA-binding death effector domain-containing protein 2 (226-276) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DEDD2 |
| Gene ID | 162989 |
| Uniprot ID | DEDD2_HUMAN |
| Immunogen | Synthesized peptide derived from human DEDD2 AA range: 226-276 |
| Immunogen Region | 226-276 |
| Specificity | This antibody detects endogenous levels of human DEDD2 |
Additional Info
| Function | May play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the nucleus. May regulate degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. |
| Protein Name | Dna-Binding Death Effector Domain-Containing Protein 2Ded-Containing Protein Flame-3Fadd-Like Anti-Apoptotic Molecule 3 |
| Database Links | |
| Cellular Localisation | NucleusNucleolusNuclearAccumulated In Subnuclear Structures Resembling Nucleoli |
| Alternative Antibody Names | Anti-Dna-Binding Death Effector Domain-Containing Protein 2 antibodyAnti-Ded-Containing Protein Flame-3 antibodyAnti-Fadd-Like Anti-Apoptotic Molecule 3 antibodyAnti-DEDD2 antibodyAnti-FLAME3 antibodyAnti-PSEC0004 antibody |
Information sourced from Uniprot.org