Anti-DDX6 antibody (433-483) (STJ500744)

Name: Anti-DDX6 antibody (433-483) (STJ500744)
SKU: STJ500744-100
Price: 400.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

ImmunogenSynthetic peptide taken within amino acid region 433-483 on probable ATP-dependent RNA helicase DDX6 protein.

STJ500744-100

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Short Description	Rabbit polyclonal antibody anti-DDX6 (433-483) is suitable for use in Dot Blot, ELISA, Immunoprecipitation and Western Blot research applications.
Applications	DB/ELISA/IP/WB
Host	Rabbit
Reactivity	Chicken/Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	0.68-0.70 µg/µl
Purification	Affinity Purified
Dilution Range	WB: 1:500 DB: 1:4, 000 ELISA: 1:4, 000 IP: 1:150
Formulation	Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Storage Instruction	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol	DDX6
Gene ID	1656
Uniprot ID	DDX6_HUMAN
Immunogen	Synthetic peptide taken within amino acid region 433-483 on probable ATP-dependent RNA helicase DDX6 protein.
Immunogen Region	433-483

Tissue Specificity	Abundantly expressed in most tissues.
Post Translational Modifications	Sumoylated.
Function	Essential for the formation of P-bodies, cytosolic membrane-less ribonucleoprotein granules involved in RNA metabolism through the coordinated storage of mRNAs encoding regulatory functions. Plays a role in P-bodies to coordinate the storage of translationally inactive mRNAs in the cytoplasm and prevent their degradation. In the process of mRNA degradation, plays a role in mRNA decapping. Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degradation of their transcripts.
Protein Name	Probable Atp-Dependent Rna Helicase Ddx6 Atp-Dependent Rna Helicase P54 Dead Box Protein 6 Oncogene Rck
Database Links	Reactome: R-HSA-430039
Cellular Localisation	Cytoplasm P-Body Nucleus Cytoplasmic Ribonucleoprotein Granule Imported In The Nucleus Via Interaction With Eif4enif1/4e-T Via A Piggy-Back Mechanism Upon Cellular Stress Relocalizes To Stress Granules
Alternative Antibody Names	Anti-Probable Atp-Dependent Rna Helicase Ddx6 antibody Anti-Atp-Dependent Rna Helicase P54 antibody Anti-Dead Box Protein 6 antibody Anti-Oncogene Rck antibody Anti-DDX6 antibody Anti-HLR2 antibody Anti-RCK antibody

Information sourced from Uniprot.org