Anti-DDX6 antibody (433-483) {Biotin} (STJ500745)

SKU:
STJ500745-100

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Host: Rabbit
Applications: DB/ELISA/IP/WB
Reactivity: Chicken/Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-DDX6 (433-483) is suitable for use in Dot Blot, ELISA, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Biotin
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.68-0.70 µg/µl
Dilution Range: WB: 1:500
DB: 1:4, 000
ELISA: 1:4, 000
IP: 1:150
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: DDX6
Gene ID: 1656
Uniprot ID: DDX6_HUMAN
Immunogen Region: 433-483
Immunogen: Synthetic peptide taken within amino acid region 433-483 on probable ATP-dependent RNA helicase DDX6 protein.
Tissue Specificity Abundantly expressed in most tissues.
Post Translational Modifications Sumoylated.
Function Essential for the formation of P-bodies, cytosolic membrane-less ribonucleoprotein granules involved in RNA metabolism through the coordinated storage of mRNAs encoding regulatory functions. Plays a role in P-bodies to coordinate the storage of translationally inactive mRNAs in the cytoplasm and prevent their degradation. In the process of mRNA degradation, plays a role in mRNA decapping. Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degradation of their transcripts.
Protein Name Probable Atp-Dependent Rna Helicase Ddx6
Atp-Dependent Rna Helicase P54
Dead Box Protein 6
Oncogene Rck
Database Links Reactome: R-HSA-430039
Cellular Localisation Cytoplasm
P-Body
Nucleus
Imported In The Nucleus Via Interaction With Eif4enif1/4e-T Via A Piggy-Back Mechanism
Upon Cellular Stress
Relocalizes To Stress Granules
Alternative Antibody Names Anti-Probable Atp-Dependent Rna Helicase Ddx6 antibody
Anti-Atp-Dependent Rna Helicase P54 antibody
Anti-Dead Box Protein 6 antibody
Anti-Oncogene Rck antibody
Anti-DDX6 antibody
Anti-HLR2 antibody
Anti-RCK antibody

Information sourced from Uniprot.org

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