Anti-DDX47 antibody (186-455) (STJ112396)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal DDX47 (186-455) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DDX47 |
| Gene ID | 51202 |
| Uniprot ID | DDX47_HUMAN |
| Immunogen Region | 186-455 |
| Immunogen Sequence | TEVDKILKVIPRDRKTFLFS ATMTKKVQKLQRAALKNPVK CAVSSKYQTVEKLQQYYIFI PSKFKDTYLVYILNELAGNS FMIFCSTCNNTQRTALLLRN LGFTAIPLHGQMSQSKRLGS LNKFKAKARSILLATDVASR GLDIPHVDVVVNFDIPTHSK DYIHRVGRTARAGRSGKAIT FVTQYDVELFQRIEHLIGKK LPGFPTQDDEVMMLTERVAE AQRFARMELREHGEKKKRS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 186-455 of human DDX47 (NP_057439.2). |
Additional Info
| Tissue Specificity | Expressed in skin, lung and breast. Also expressed in the brain. |
| Function | Required for efficient ribosome biogenesis. May have a role in mRNA splicing. Involved in apoptosis. |
| Protein Name | Probable Atp-Dependent Rna Helicase Ddx47Dead Box Protein 47 |
| Database Links | Reactome: R-HSA-6790901Reactome: R-HSA-6791226 |
| Cellular Localisation | NucleusNucleolusLocalizes In The Nucleolar-Organizing Region During Ribosome Biogenesis |
| Alternative Antibody Names | Anti-Probable Atp-Dependent Rna Helicase Ddx47 antibodyAnti-Dead Box Protein 47 antibodyAnti-DDX47 antibody |
Information sourced from Uniprot.org