Anti-DDX3Y antibody (1-210) (STJ113303)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal DDX3Y (1-210) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:100IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20Β°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DDX3Y |
| Gene ID | 8653 |
| Uniprot ID | DDX3Y_HUMAN |
| Immunogen Region | 1-210 |
| Immunogen Sequence | MSHVVVKNDPELDQQLANLD LNSEKQSGGASTASKGRYIP PHLRNREASKGFHDKDSSGW SCSKDKDAYSSFGSRDSRGK PGYFSERGSGSRGRFDDRGR SDYDGIGNRERPGFGRFERS GHSRWCDKSVEDDWSKPLPP SERLEQELFSGGNTGINFEK YDDIPVEATGSNCPPHIENF SDIDMGEIIMGNIELTRYTR PTPVQKHAIP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human DDX3Y (NP_001116137.1). |
Additional Info
| Tissue Specificity | Widely expressed at the mRNA level, with highest levels in testis. Testis-specific (at protein level). Expressed predominantly in spermatogonia, but occasionally detected in some pre-leptotene/leptotene spermatocytes. |
| Function | Probable ATP-dependent RNA helicase. During immune response, may enhance IFNB1 expression via IRF3/IRF7 pathway. |
| Protein Name | Atp-Dependent Rna Helicase Ddx3yDead Box Protein 3 - Y-Chromosomal |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusShuttles Between The Nucleus And The Cytoplasm In An Xpo1-Dependent Manner |
| Alternative Antibody Names | Anti-Atp-Dependent Rna Helicase Ddx3y antibodyAnti-Dead Box Protein 3 - Y-Chromosomal antibodyAnti-DDX3Y antibodyAnti-DBY antibody |
Information sourced from Uniprot.org