| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Probable ATP-dependent RNA helicase DDX23 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DDX23 |
| Gene ID: |
9416 |
| Uniprot ID: |
DDX23_HUMAN |
| Specificity: |
This antibody detects endogenous levels of DDX23 at Human |
| Immunogen: |
Synthesized peptide derived from human DDX23 |
| Function | Involved in pre-mRNA splicing and its phosphorylated form (by SRPK2) is required for spliceosomal B complex formation. Independently of its spliceosome formation function, required for the suppression of incorrect R-loops formed during transcription.R-loops are composed of a DNA:RNA hybrid and the associated non-template single-stranded DNA. |
| Protein Name | Probable Atp-Dependent Rna Helicase Ddx23100 Kda U5 Snrnp-Specific ProteinDead Box Protein 23Prp28 HomologU5-100kd |
| Database Links | Reactome: R-HSA-72163Reactome: R-HSA-72165 |
| Cellular Localisation | NucleusChromosomeDuring TranscriptionAccumulates At Chromatin Loci Where Unscheduled R-Loops Form And Colocalizes With Paused 'Ser-5'-Phosphorlyated Polr2a/Rna Polymerase Ii And Kinase Srpk2 |
| Alternative Antibody Names | Anti-Probable Atp-Dependent Rna Helicase Ddx23 antibodyAnti-100 Kda U5 Snrnp-Specific Protein antibodyAnti-Dead Box Protein 23 antibodyAnti-Prp28 Homolog antibodyAnti-U5-100kd antibodyAnti-DDX23 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
