Anti-DCT antibody (50-350) (STJ118481)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal DCT (50-350) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DCT |
| Gene ID | 1638 |
| Uniprot ID | TYRP2_HUMAN |
| Immunogen Region | 50-350 |
| Immunogen Sequence | NVCGSQQGRGQCTEVRADTR PWSGPYILRNQDDRELWPRK FFHRTCKCTGNFAGYNCGDC KFGWTGPNCERKKPPVIRQN IHSLSPQEREQFLGALDLAK KRVHPDYVITTQHWLGLLGP NGTQPQFANCSVYDFFVWLH YYSVRDTLLGPGRPYRAIDF SHQGPAFVTWHRYHLLCLER DLQRLIGNESFALPYWNFAT GRNECDVCTDQLFGAARPDD PTLISRNSRFSSWETVCDS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 50-350 of human DCT (NP_001913.2). |
Additional Info
| Post Translational Modifications | Glycosylated. |
| Function | Plays a role in melanin biosynthesis. Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA). |
| Protein Name | L-Dopachrome TautomeraseDctDtL-Dopachrome Delta-IsomeraseTyrosinase-Related Protein 2Trp-2Trp2 |
| Database Links | Reactome: R-HSA-5662702Reactome: R-HSA-9824585 |
| Cellular Localisation | Melanosome MembraneSingle-Pass Type I Membrane ProteinMelanosomeProper Trafficking To Melanosome Is Regulated By Sgsm2Ankrd27Rab9aRab32 And Rab38 |
| Alternative Antibody Names | Anti-L-Dopachrome Tautomerase antibodyAnti-Dct antibodyAnti-Dt antibodyAnti-L-Dopachrome Delta-Isomerase antibodyAnti-Tyrosinase-Related Protein 2 antibodyAnti-Trp-2 antibodyAnti-Trp2 antibodyAnti-DCT antibodyAnti-TYRP2 antibody |
Information sourced from Uniprot.org