Anti-DcR1/CD263 antibody [SRM13428] (STJ11108158)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal Tumor Necrosis Factor Receptor Superfamily Member 10c antibody for use in WB, IHC-P, FC and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/FC/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM13428 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB, 1:1000-1:5000IHC-P, 1:50-1:200FC, 1:100-1:500ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS containing 50% Glycerol and 0.05% BSA, preserved with proclin300 or Sodium Azide (as specified on the Certificate of Analysis) , pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TNFRSF10C |
| Gene ID | 8794 |
| Uniprot ID | TR10C_HUMAN |
| Immunogen | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Immunogen Sequence | Human |
Additional Info
| Post Translational Modifications | N-glycosylated and O-glycosylated. |
| Function | Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 10cAntagonist Decoy Receptor For Trail/Apo-2lDecoy Trail Receptor Without Death DomainDecoy Receptor 1Dcr1Lymphocyte Inhibitor Of TrailTnf-Related Apoptosis-Inducing Ligand Receptor 3Trail Receptor 3Trail-R3Trail Receptor Without An Intracellular DomainCd Antigen Cd263 |
| Database Links | Reactome: R-HSA-6803211 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 10c antibodyAnti-Antagonist Decoy Receptor For Trail/Apo-2l antibodyAnti-Decoy Trail Receptor Without Death Domain antibodyAnti-Decoy Receptor 1 antibodyAnti-Dcr1 antibodyAnti-Lymphocyte Inhibitor Of Trail antibodyAnti-Tnf-Related Apoptosis-Inducing Ligand Receptor 3 antibodyAnti-Trail Receptor 3 antibodyAnti-Trail-R3 antibodyAnti-Trail Receptor Without An Intracellular Domain antibodyAnti-Cd Antigen Cd263 antibodyAnti-TNFRSF10C antibodyAnti-DCR1 antibodyAnti-LIT antibodyAnti-TRAILR3 antibodyAnti-TRID antibodyAnti-UNQ321 antibodyAnti-PRO366 antibody |
Information sourced from Uniprot.org