Anti-DCP1B antibody (386-617) (STJ11103182)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal DCP1B (386-617) antibody for use in WB and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DCP1B |
| Gene ID | 196513 |
| Uniprot ID | DCP1B_HUMAN |
| Immunogen Region | 386-617 |
| Immunogen Sequence | RAPTSVTPVAPGKGLAQPPQ AYFNGSLPPQTVGHQAHGRE QSTLPRQTLPISGSQTGSSG VISPQELLKKLQIVQQEQQL HASNRPALAAKFPVLAQSSG TGKPLESWINKTPNTEQQTP LFQVISPQRIPATAAPSLLM SPMVFAQPTSVPPKERESGL LPVGGQEPPAAATSLLLPIQ SPEPSVITSSPLTKLQLQEA LLYLIQNDDNFLNIIYEAYL FSMTQAAMKKTM |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 386-617 of human DCP1B (NP_689853.3). |
Additional Info
| Function | May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. |
| Protein Name | Mrna-Decapping Enzyme 1b |
| Database Links | Reactome: R-HSA-430039 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Mrna-Decapping Enzyme 1b antibodyAnti-DCP1B antibody |
Information sourced from Uniprot.org