Anti-DCLK1 antibody (590-740) (STJ113645)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal DCLK1 (590-740) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DCLK1 |
| Gene ID | 9201 |
| Uniprot ID | DCLK1_HUMAN |
| Immunogen Region | 590-740 |
| Immunogen Sequence | SGDDQEVLFDQILMGQVDFP SPYWDNVSDSAKELITMMLL VDVDQRFSAVQVLEHPWVND DGLPENEHQLSVAGKIKKHF NTGPKPNSTAAGVSVIATTA LDKERQVFRRRRNQDVRSRY KAQPAPPELNSESEDYSPSS SETVRSPNSPF |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 590-740 of DCAMKL1/DCLK1 (NP_001317000.1). |
Additional Info
| Tissue Specificity | In fetal tissues, highly expressed in brain, detectable in lung and liver, but not in kidney. In adult tissues, expressed ubiquitously in the brain, detectable in the heart, liver, spleen, thymus, prostate, testis, ovary, small intestine and colon. The type A isoforms seem to be expressed predominantly in fetal brain whereas type B isoforms are expressed abundantly in both fetal and adult brain. |
| Function | Probable kinase that may be involved in a calcium-signaling pathway controlling neuronal migration in the developing brain. May also participate in functions of the mature nervous system. |
| Protein Name | Serine/Threonine-Protein Kinase Dclk1Doublecortin Domain-Containing Protein 3aDoublecortin-Like And Cam Kinase-Like 1Doublecortin-Like Kinase 1 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Kinase Dclk1 antibodyAnti-Doublecortin Domain-Containing Protein 3a antibodyAnti-Doublecortin-Like And Cam Kinase-Like 1 antibodyAnti-Doublecortin-Like Kinase 1 antibodyAnti-DCLK1 antibodyAnti-DCAMKL1 antibodyAnti-DCDC3A antibodyAnti-KIAA0369 antibody |
Information sourced from Uniprot.org