| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DCDC2 (1-250) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DCDC2 |
| Gene ID: |
51473 |
| Uniprot ID: |
DCDC2_HUMAN |
| Immunogen Region: |
1-250 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human DCDC2 (NP_001182539). |
| Immunogen Sequence: |
MSGSSARSSHLSQPVVKSVL VYRNGDPFYAGRRVVIHEKK VSSFEVFLKEVTGGVQAPFG AVRNIYTPRTGHRIRKLDQI QSGGNYVAGGQEAFKKLNYL DIGEIKKRPMEVVNTEVKPV IHSRINVSARFRKPLQEPCT IFLIANGDLINPASRLLIPR KTLNQWDHVLQMVTEKITLR SGAVHRLYTLEGKLVESGAE LENGQFYVAVGRDKFKKLPY SELLFDKSTMRRPFGQKAS |
| Tissue Specificity | Ubiquitously expressed. In brain, highly expressed in the entorhinal cortex, inferior temporal cortex, medial temporal cortex, hypothalamus, amygdala and hippocampus. Expressed in liver by cholangiocytes, the epithelial cells of the bile ducts (at protein level). |
| Function | Protein that plays a role in the inhibition of canonical Wnt signaling pathway. May be involved in neuronal migration during development of the cerebral neocortex. Involved in the control of ciliogenesis and ciliary length. |
| Protein Name | Doublecortin Domain-Containing Protein 2Protein Ru2s |
| Cellular Localisation | Cell ProjectionCiliumCytoplasmCytoskeletonCilium AxonemeKinociliumLocalizes To The Ciliary Axoneme And To Mitotic Spindle Fibers In A Cell-Cycle-Dependent Manner |
| Alternative Antibody Names | Anti-Doublecortin Domain-Containing Protein 2 antibodyAnti-Protein Ru2s antibodyAnti-DCDC2 antibodyAnti-KIAA1154 antibodyAnti-RU2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
