Anti-DCDC2 antibody (1-250) (STJ119747)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal DCDC2 (1-250) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DCDC2 |
| Gene ID | 51473 |
| Uniprot ID | DCDC2_HUMAN |
| Immunogen Region | 1-250 |
| Immunogen Sequence | MSGSSARSSHLSQPVVKSVL VYRNGDPFYAGRRVVIHEKK VSSFEVFLKEVTGGVQAPFG AVRNIYTPRTGHRIRKLDQI QSGGNYVAGGQEAFKKLNYL DIGEIKKRPMEVVNTEVKPV IHSRINVSARFRKPLQEPCT IFLIANGDLINPASRLLIPR KTLNQWDHVLQMVTEKITLR SGAVHRLYTLEGKLVESGAE LENGQFYVAVGRDKFKKLPY SELLFDKSTMRRPFGQKAS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human DCDC2 (NP_001182539). |
Additional Info
| Tissue Specificity | Ubiquitously expressed. In brain, highly expressed in the entorhinal cortex, inferior temporal cortex, medial temporal cortex, hypothalamus, amygdala and hippocampus. Expressed in liver by cholangiocytes, the epithelial cells of the bile ducts (at protein level). |
| Function | Protein that plays a role in the inhibition of canonical Wnt signaling pathway. May be involved in neuronal migration during development of the cerebral neocortex. Involved in the control of ciliogenesis and ciliary length. |
| Protein Name | Doublecortin Domain-Containing Protein 2Protein Ru2s |
| Database Links | |
| Cellular Localisation | Cell ProjectionCiliumCytoplasmCytoskeletonCilium AxonemeKinociliumLocalizes To The Ciliary Axoneme And To Mitotic Spindle Fibers In A Cell-Cycle-Dependent Manner |
| Alternative Antibody Names | Anti-Doublecortin Domain-Containing Protein 2 antibodyAnti-Protein Ru2s antibodyAnti-DCDC2 antibodyAnti-KIAA1154 antibodyAnti-RU2 antibody |
Information sourced from Uniprot.org