Anti-DBNL antibody (STJA0007352)

SKU:
STJA0007352

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Drebrin-like protein is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DBNL
Gene ID: 28988
Uniprot ID: DBNL_HUMAN
Specificity: This antibody detects endogenous levels of DBNL at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human DBNL
Function Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G-actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes. May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes.
Protein Name Drebrin-Like Protein
Cervical Sh3p7
Cervical Mucin-Associated Protein
Drebrin-F
Hpk1-Interacting Protein Of 55 Kda
Hip-55
Sh3 Domain-Containing Protein 7
Database Links Reactome: R-HSA-264870
Reactome: R-HSA-6794361
Reactome: R-HSA-6798695
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Projection
Lamellipodium
Ruffle
Cell Cortex
Cytosol
Synapse
Perikaryon
Neuron Projection
Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Cytoplasmic Vesicle
Clathrin-Coated Vesicle Membrane
Golgi Apparatus Membrane
Podosome
Early Endosome
Dendrite
Postsynaptic Density
Associates With Lamellipodial Actin And Membrane Ruffles
Colocalizes With Actin And Cortactin At Podosome Dots And Podosome Rosettes
Alternative Antibody Names Anti-Drebrin-Like Protein antibody
Anti-Cervical Sh3p7 antibody
Anti-Cervical Mucin-Associated Protein antibody
Anti-Drebrin-F antibody
Anti-Hpk1-Interacting Protein Of 55 Kda antibody
Anti-Hip-55 antibody
Anti-Sh3 Domain-Containing Protein 7 antibody
Anti-DBNL antibody
Anti-CMAP antibody
Anti-SH3P7 antibody
Anti-PP5423 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance