Anti-DBH antibody (401-450 aa) (STJ92661)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human DBH at the amino acid range 401-450
General Information
| Short Description | Rabbit polyclonal anti-Dopamine beta-hydroxylase (401-450 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DBH |
| Gene ID | 1621 |
| Uniprot ID | DOPO_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human DBH at the amino acid range 401-450 |
| Immunogen Region | 401-450 aa |
| Specificity | DBH Polyclonal Antibody detects endogenous levels of DBH protein. |
Additional Info
| Function | Catalyzes the hydroxylation of dopamine to noradrenaline (also known as norepinephrine), and is thus vital for regulation of these neurotransmitters. |
| Protein Name | Dopamine Beta-HydroxylaseDopamine Beta-Monooxygenase Cleaved Into - Soluble Dopamine Beta-Hydroxylase |
| Database Links | Reactome: R-HSA-209905 |
| Cellular Localisation | Soluble Dopamine Beta-Hydroxylase: Cytoplasmic VesicleSecretory Vesicle LumenCytoplasmic VesicleSecretory VesicleChromaffin Granule LumenSecretedSecretory Vesicle MembraneSingle-Pass Type Ii Membrane ProteinChromaffin Granule Membrane |
| Alternative Antibody Names | Anti-Dopamine Beta-Hydroxylase antibodyAnti-Dopamine Beta-Monooxygenase Cleaved Into - Soluble Dopamine Beta-Hydroxylase antibodyAnti-DBH antibody |
Information sourced from Uniprot.org