| Short Description : | Goat polyclonal antibody anti-Dbf4-Mouse (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications: | Pep-ELISA/WB |
| Host: | Goat |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 70kDa band observed in Mouse and Rat Testis and Thymus lysates (calculated MW of 74.2kDa according to NP_038754.1). Recommended concentration: 1-3µg/ml. |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Accession Number: | NP_038754.1; NP_001177646.1 |
| Immunogen Region: | Internal |
| Immunogen Sequence: | DKKRTEYLPAHEDRT |
| Specificity: | This antibody is expected to recognize both reported isoforms (NP_038754.1; NP_001177646.1). |
| Function | Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role DNA in replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle. |
| Protein Name | Protein Dbf4 Homolog AMudbf4 |
| Database Links | Reactome: R-MMU-176187Reactome: -MMU-68962 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Protein Dbf4 Homolog A antibodyAnti-Mudbf4 antibodyAnti-Dbf4 antibodyAnti-Dbf4a antibody |
Information sourced from Uniprot.org
