Anti-DAP antibody (11-60 aa) (STJ92650)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human DAP at the amino acid range 11-60
General Information
| Short Description | Rabbit polyclonal anti-Death-associated protein 1 (11-60 aa) for use in IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DAP |
| Gene ID | 1611 |
| Uniprot ID | DAP1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human DAP at the amino acid range 11-60 |
| Immunogen Region | 11-60 aa |
| Specificity | DAP-1 Polyclonal Antibody detects endogenous levels of DAP-1 protein. |
Additional Info
| Function | Ribosome-binding protein involved in ribosome hibernation, a process during which ribosomes are stabilized in an inactive state and preserved from proteasomal degradation. Acts via its association with eiF5a (EIF5A and EIF5A2) at the polypeptide exit tunnel of the ribosome, preventing mRNA translation. Involved in ribosome hibernation in the mature oocyte by preventing mRNA translation, leading to ribosome inactivation. Ribosomes, which are produced in large quantities during oogenesis, are stored and translationally repressed in the oocyte and early embryo. Also acts as a negative regulator of autophagy. Involved in mediating interferon-gamma-induced cell death. |
| Protein Name | Death-Associated Protein 1Dap-1 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Death-Associated Protein 1 antibodyAnti-Dap-1 antibodyAnti-DAP antibodyAnti-DAP1 antibody |
Information sourced from Uniprot.org