| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-D2HGDH (322-521) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
D2HGDH |
| Gene ID: |
728294 |
| Uniprot ID: |
D2HDH_HUMAN |
| Immunogen Region: |
322-521 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 322-521 of human D2HGDH (NP_689996.4). |
| Immunogen Sequence: |
GRHLHLASPVQESPFYVLIE TSGSNAGHDAEKLGHFLEHA LGSGLVTDGTMATDQRKVKM LWALRERITEALSRDGYVYK YDLSLPVERLYDIVTDLRAR LGPHAKHVVGYGHLGDGNLH LNVTAEAFSPSLLAALEPHV YEWTAGQQGSVSAEHGVGFR KRDVLGYSKPPGALQLMQQL KALLDPKGILNPYKTLPSQA |
| Function | Catalyzes the oxidation of D-2-hydroxyglutarate (D-2-HG) to alpha-ketoglutarate. Also catalyzes the oxidation of other D-2-hydroxyacids, such as D-malate (D-MAL) and D-lactate (D-LAC). Exhibits high activities towards D-2-HG and D-MAL but a very weak activity towards D-LAC. |
| Protein Name | D-2-Hydroxyglutarate Dehydrogenase - Mitochondrial |
| Database Links | Reactome: R-HSA-880009 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-D-2-Hydroxyglutarate Dehydrogenase - Mitochondrial antibodyAnti-D2HGDH antibodyAnti-D2HGD antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
