Anti-Cytokeratin 8&18 antibody [B22.1+B23.1] (STJ16100355)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
STJ16100355
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General Information

Short DescriptionMouse monoclonal anti-Cytokeratin 8&18 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsIHC-P
HostMouse
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDB22.1+B23.1
IsotypeIgG1
ConjugationUnconjugated
Dilution RangeIHC 1: 100 – 1:500
FormulationTris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Storage InstructionStore at 2-8°C for up to 1-year, upon receipt.

Target Information

Additional Info

Background Cytokeratins 8 &18 (CK 8 & 18) are expressed in most simple epithelia (e.g. thyroid, breast, gastrointestinal tract, and respiratory tract). Anti-CK 8 & 18 have been reported to stain most adenocarcinomas and squamous cell carcinomas, but not some well-differentiated squamous cell carcinomas. Cytokeratin 8 & 18 have been reported to be useful markers for identifying Paget cells, colorectal carcinoma metastases, 5 and gastric cancer micro metastases.

Information sourced from Uniprot.org

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