| Short Description : | Rabbit monoclonal Cytokeratin 7 (Full Length) antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC-P |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | ZR428 |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | Affinity purified |
| Dilution Range: | 1:100-200 |
| Formulation: | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Storage Instruction: | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
| Gene Symbol: | KRT7 |
| Gene ID: | 3855 |
| Uniprot ID: | K2C7_HUMAN |
| Immunogen: | Recombinant full-length human KRT7 protein |
| Immunogen Region: | Full Length |
| Specificity: | Positive Control: Ovarian carcinoma |
| Tissue Specificity | Expressed in cultured epidermal, bronchial and mesothelial cells but absent in colon, ectocervix and liver. Observed throughout the glandular cells in the junction between stomach and esophagus but is absent in the esophagus. |
| Post Translational Modifications | Arg-20 is dimethylated, probably to asymmetric dimethylarginine. |
| Function | Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). |
| Protein Name | Keratin - Type Ii Cytoskeletal 7Cytokeratin-7Ck-7Keratin-7K7SarcolectinType-Ii Keratin Kb7 |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Keratin - Type Ii Cytoskeletal 7 antibodyAnti-Cytokeratin-7 antibodyAnti-Ck-7 antibodyAnti-Keratin-7 antibodyAnti-K7 antibodyAnti-Sarcolectin antibodyAnti-Type-Ii Keratin Kb7 antibodyAnti-KRT7 antibodyAnti-SCL antibody |
Information sourced from Uniprot.org
