![Anti-Cytokeratin 5&6 antibody [D5/16B4] (STJ16100353)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/149070/346688/STJ16100353_1__77588.1681998770.jpg?c=1 "Anti-Cytokeratin 5&6 antibody [D5/16B4] (STJ16100353)")
![Anti-Cytokeratin 5&6 antibody [D5/16B4] (STJ16100353)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/149070/346688/STJ16100353_1__77588.1681998770.jpg?c=1 "Anti-Cytokeratin 5&6 antibody [D5/16B4] (STJ16100353)")
Anti-Cytokeratin 5&6 antibody [D5/16B4] (STJ16100353)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
General Information
| Short Description | Mouse monoclonal anti-Cytokeratin 5&6 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | D5/16B4 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Dilution Range | IHC 1: 50 – 1:200 |
| Formulation | Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
Additional Info
| Background | Anti-CK 5/6 positivity is seen in nearly 100% of malignant mesotheliomas and in nearly 0% of lung adenocarcinomas. Anti-CK 5/6 positivity can be seen in undifferentiated large cell carcinoma as well as squamous carcinoma, and has been useful in recognizing spindle cell squamous cell carcinoma of the skin. Less than 10% of carcinomas of the breast, colon, and prostate stain positively for this marker. Anti-CK 5/6 has also been used successfully as a myoepithelial cell marker in the prostate and breast to determine malignancy. |
Information sourced from Uniprot.org