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Anti-cytokeratin 20 antibody (48-60) (STJ72886)

STJ72886 (0. 03µg/ml) staining of Human Colon lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-cytokeratin 20 antibody (48-60) (STJ72886)

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STJ72886-100

£303.50

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General Information
Product Properties
Target Information
Additional Info
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Host:	Goat
Applications:	Pep-ELISA/WB/IHC
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Goat polyclonal antibody anti-cytokeratin 20 (48-60) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	0.5 mg/mL
Dilution Range:	WB-0.01-0.03µg/ml IHC-5µg/ml ELISA-antibody detection limit dilution 1:128000.
Storage Instruction:	Store at-20°C on receipt and minimise freeze-thaw cycles.

Gene Symbol:	KRT20
Gene ID:	54474
Uniprot ID:	K1C20_HUMAN
Immunogen Region:	48-60
Accession Number:	NP_061883.1
Immunogen Sequence:	NSRHTVNYGSDLT

Post Translational Modifications	Hyperphosphorylation at Ser-13 occurs during the early stages of apoptosis but becomes less prominent during the later stages. Phosphorylation at Ser-13 also increases in response to stress brought on by cell injury. Proteolytically cleaved by caspases during apoptosis. Cleavage occurs at Asp-228.
Function	Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine.
Protein Name	Keratin - Type I Cytoskeletal 20 Cytokeratin-20 Ck-20 Keratin-20 K20 Protein It
Database Links	Reactome: R-HSA-6805567 Reactome: R-HSA-6809371
Cellular Localisation	Cytoplasm
Alternative Antibody Names	Anti-Keratin - Type I Cytoskeletal 20 antibody Anti-Cytokeratin-20 antibody Anti-Ck-20 antibody Anti-Keratin-20 antibody Anti-K20 antibody Anti-Protein It antibody Anti-KRT20 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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