• Anti-Cytokeratin 14 antibody [EP1601Y+LL002] (STJ16101645)

Anti-Cytokeratin 14 antibody [EP1601Y+LL002] (STJ16101645)

SKU:
STJ16101645-7

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Host: Rabbit, Mouse
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit, Mouse monoclonal antibody anti-Cytokeratin 14 is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: EP1601Y+LL002
Conjugation: Unconjugated
Isotype: IgG/IgG3
Formulation: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Storage Instruction: Store at 2-8°C upon receipt.
Background Cytokeratin 5 is an intermediate filament protein of 58 kD amongst the cytokeratin family. It is a type II (basic) cytokeratin. Antibodies to this protein identify basal cells of squamous and glandular epithelia, myoepithelia, and mesothelium.1 Cytokeratin 14 is a 50 kD polypeptide found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells.1 Anti-cytokeratin 5 has been useful in the differential diagnosis of metastatic carcinoma in the pleura versus epithelial mesothelioma.2 Anti-cytokeratin 14 has been demonstrated to be useful in differentiating squamous cell carcinomas from other epithelial tumors.3, 4 Anti-Cytokeratin 5, along with anti-cytokeratin 14, has been found to have an application in identifying the basal-like phenotype of breast carcinoma.5

Information sourced from Uniprot.org

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