Anti-Cytokeratin 1 antibody [BP6077] (STJA0037632)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human KRT1
General Information
| Short Description | Rabbit monoclonal anti-Cytokeratin 1 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | BP6077 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | IHC 1:100-1:200 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | KRT1 |
| Gene ID | 3848 |
| Uniprot ID | K2C1_HUMAN |
| Immunogen | A synthesized peptide derived from human KRT1 |
Additional Info
| Tissue Specificity | The source of this protein is neonatal foreskin. The 67-kDa type II keratins are expressed in terminally differentiating epidermis. |
| Post Translational Modifications | Undergoes deimination of some arginine residues (citrullination). |
| Function | May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK. |
| Protein Name | Keratin - Type Ii Cytoskeletal 167 Kda CytokeratinCytokeratin-1Ck-1Hair Alpha ProteinKeratin-1K1Type-Ii Keratin Kb1 |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-6805567Reactome: R-HSA-6809371Reactome: R-HSA-9725554 |
| Cellular Localisation | Cell MembraneCytoplasm |
| Alternative Antibody Names | Anti-Keratin - Type Ii Cytoskeletal 1 antibodyAnti-67 Kda Cytokeratin antibodyAnti-Cytokeratin-1 antibodyAnti-Ck-1 antibodyAnti-Hair Alpha Protein antibodyAnti-Keratin-1 antibodyAnti-K1 antibodyAnti-Type-Ii Keratin Kb1 antibodyAnti-KRT1 antibodyAnti-KRTA antibody |
Information sourced from Uniprot.org