Anti-CYSLTR1 antibody (131-180 aa) (STJ92608)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human CYSLTR1 at the amino acid range 131-180
General Information
| Short Description | Rabbit polyclonal anti-Cysteinyl leukotriene receptor 1 (131-180 aa) for use in WB, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:5000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CYSLTR1 |
| Gene ID | 10800 |
| Uniprot ID | CLTR1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human CYSLTR1 at the amino acid range 131-180 |
| Immunogen Region | 131-180 aa |
| Specificity | CysLTR1 Polyclonal Antibody detects endogenous levels of CysLTR1 protein. |
Additional Info
| Function | Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4. |
| Protein Name | Cysteinyl Leukotriene Receptor 1Cysltr1Cysteinyl Leukotriene D4 ReceptorLtd4 ReceptorG-Protein Coupled Receptor Hg55Hmtmf81 |
| Database Links | Reactome: R-HSA-391906Reactome: R-HSA-416476Reactome: R-HSA-9664535Reactome: R-HSA-9679191 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Cysteinyl Leukotriene Receptor 1 antibodyAnti-Cysltr1 antibodyAnti-Cysteinyl Leukotriene D4 Receptor antibodyAnti-Ltd4 Receptor antibodyAnti-G-Protein Coupled Receptor Hg55 antibodyAnti-Hmtmf81 antibodyAnti-CYSLTR1 antibodyAnti-CYSLT1 antibody |
Information sourced from Uniprot.org