Host: |
Rabbit |
Applications: |
WB/IF/ELISA |
Reactivity: |
Human/Rat/Mouse/Chicken |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Cytochrome P450 2A6 (1-50 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IF 1:200-1:1000ELISA 1:20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
CYP2A6 |
Gene ID: |
1548 |
Uniprot ID: |
CP2A6_HUMAN |
Immunogen Region: |
1-50 aa |
Specificity: |
CYP2A6 Polyclonal Antibody detects endogenous levels of CYP2A6 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human Cytochrome P450 2A6 at the amino acid range 1-50 |
Function | Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4-cineole 2-exo-monooxygenase. Possesses low phenacetin O-deethylation activity. |
Protein Name | Cytochrome P450 2a61 -4-Cineole 2-Exo-MonooxygenaseCypiia6Coumarin 7-HydroxylaseCytochrome P450 Iia3Cytochrome P450(I |
Database Links | Reactome: R-HSA-211981Reactome: R-HSA-211999 |
Cellular Localisation | Endoplasmic Reticulum MembranePeripheral Membrane ProteinMicrosome Membrane |
Alternative Antibody Names | Anti-Cytochrome P450 2a6 antibodyAnti-1 -4-Cineole 2-Exo-Monooxygenase antibodyAnti-Cypiia6 antibodyAnti-Coumarin 7-Hydroxylase antibodyAnti-Cytochrome P450 Iia3 antibodyAnti-Cytochrome P450(I antibodyAnti-CYP2A6 antibodyAnti-CYP2A3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance