• Anti-Cyclin D1 antibody [P2D11F11] (STJ16101725)

Anti-Cyclin D1 antibody [P2D11F11] (STJ16101725)

SKU:
STJ16101725-1

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Host: Mouse
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Cyclin D1 is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: P2D11F11
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: Tissue culture supernatant with Sodium azide
Concentration: >=19 mg/L
Dilution Range: IHC-P 1:50
Storage Instruction: Store at 2-8°C upon receipt.
Immunogen: Prokaryotic fusion protein corresponding to the human cyclin D1 molecule.
Background The D-type cyclins are a family of proteins which function primarily by regulating the activity of cyclin dependent kinases in the G1 phase of the cell cycle. Cyclin D1, a protein of 36 kD, is also known as PRAD1 or bcl-1. Maximum expression of cyclin D1 occurs at a critical point in mid to late G1 phase of the cell cycle. The cyclin D1 gene, located on 11q13 has been reported to be overexpressed in mantle cell lymphomas due to the chromosomal translocation t (11;18).

Information sourced from Uniprot.org

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