Anti-Cyclin D-type binding-protein 1 antibody (322-333) (STJ72741)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-Cyclin D-type binding-protein 1 (322-333) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Dog/Pig/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:4000.WB: Approx 40kDa band observed in Human Placenta lysates (calculated MW of 40.3kDa according to NP_036274.3). Recommended concentration: 0.3-1µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | CCNDBP1 |
| Gene ID | 23582 |
| Uniprot ID | CCDB1_HUMAN |
| Accession Number | NP_036274.3 |
| Immunogen Region | 322-333 |
| Immunogen Sequence | TKASHVTPQPED |
Additional Info
| Post Translational Modifications | Phosphorylated. |
| Function | May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription. |
| Protein Name | Cyclin-D1-Binding Protein 1Grap2 And Cyclin-D-Interacting ProteinHuman Homolog Of Maid |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Cyclin-D1-Binding Protein 1 antibodyAnti-Grap2 And Cyclin-D-Interacting Protein antibodyAnti-Human Homolog Of Maid antibodyAnti-CCNDBP1 antibodyAnti-DIP1 antibodyAnti-GCIP antibodyAnti-HHM antibody |
Information sourced from Uniprot.org