Anti-CYBRD1 antibody (41-91 aa) (STJ195985)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human CYBR1 at the amino acid range 41-91
General Information
| Short Description | Rabbit polyclonal anti-Plasma membrane ascorbate-dependent reductase CYBRD1 (41-91 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CYBRD1 |
| Gene ID | 79901 |
| Uniprot ID | CYBR1_HUMAN |
| Immunogen | Synthesized peptide derived from the human CYBR1 at the amino acid range 41-91 |
| Immunogen Region | 41-91 aa |
| Specificity | This antibody detects endogenous levels of CYBR1 at Human/Mouse/Rat |
Additional Info
| Function | Plasma membrane reductase that uses cytoplasmic ascorbate as an electron donor to reduce extracellular Fe(3+) into Fe(2+). Probably functions in dietary iron absorption at the brush border of duodenal enterocytes by producing Fe(2+), the divalent form of iron that can be transported into enterocytes. It is also able to reduce extracellular monodehydro-L-ascorbate and may be involved in extracellular ascorbate regeneration by erythrocytes in blood. May also act as a ferrireductase in airway epithelial cells (Probable). May also function as a cupric transmembrane reductase. |
| Protein Name | Plasma Membrane Ascorbate-Dependent Reductase Cybrd1Cytochrome B Reductase 1Duodenal Cytochrome BFerric-Chelate Reductase 3 |
| Database Links | Reactome: R-HSA-917937 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinApical Cell MembraneLocalized At The Brush Border Of Duodenal Cells |
| Alternative Antibody Names | Anti-Plasma Membrane Ascorbate-Dependent Reductase Cybrd1 antibodyAnti-Cytochrome B Reductase 1 antibodyAnti-Duodenal Cytochrome B antibodyAnti-Ferric-Chelate Reductase 3 antibodyAnti-CYBRD1 antibodyAnti-DCYTB antibodyAnti-FRRS3 antibody |
Information sourced from Uniprot.org