Anti-Cyb5r4-Mouse antibody (444-458) (STJ72782)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-Cyb5r4-Mouse (444-458) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Approx 65kDa band observed in Rat Spleen lysates (calculated MW of 55kDa according to NP_596918.2 and 58.8kDa according to Q68EJ0-1). Recommended concentration: 0.1-0.3µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Accession Number | NP_077157.2 |
| Immunogen Region | 444-458 |
| Immunogen Sequence | RCQLEKLALREKRFD |
Additional Info
| Function | NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS). |
| Protein Name | Cytochrome B5 Reductase 4Flavohemoprotein B5/B5rB5+B5rN-Terminal Cytochrome B5 And Cytochrome B5 Oxidoreductase Domain-Containing ProteinCb5/Cb5r |
| Database Links | Reactome: R-MMU-1237044 |
| Cellular Localisation | Endoplasmic ReticulumSoluble Protein |
| Alternative Antibody Names | Anti-Cytochrome B5 Reductase 4 antibodyAnti-Flavohemoprotein B5/B5r antibodyAnti-B5+B5r antibodyAnti-N-Terminal Cytochrome B5 And Cytochrome B5 Oxidoreductase Domain-Containing Protein antibodyAnti-Cb5/Cb5r antibodyAnti-Cyb5r4 antibodyAnti-Ncb5or antibody |
Information sourced from Uniprot.org