Anti-CXCR2/IL-8RB antibody {ABflo® 647} (STJ11109029)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationABflo® 647
IsotypeIgG
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal CXCR2/IL-8RB antibody for use in FC in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG |
| Conjugation | ABflo® 647 |
| Purification | Affinity purification |
| Dilution Range | FC, 5 Mu l per 10^6 cells in 100 Mu l volume |
| Formulation | PBS with 0.09% Sodium azide, 0.2% BSA, pH7.3. |
| Storage Instruction | Store at 4°C for up to 1 year from the date of receipt. Do not freeze. |
Target Information
| Gene Symbol | Cxcr2 |
| Gene ID | 12765 |
| Uniprot ID | CXCR2_MOUSE |
| Immunogen | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
Additional Info
| Post Translational Modifications | Phosphorylated upon ligand binding.which is required for desensitization. |
| Function | Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2. |
| Protein Name | C-X-C Chemokine Receptor Type 2Cxc-R2Cxcr-2Gro/Mgsa ReceptorHigh Affinity Interleukin-8 Receptor BIl-8r BCd Antigen Cd182 |
| Database Links | Reactome: R-MMU-380108Reactome: -MMU-418594Reactome: -MMU-6798695 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-C-X-C Chemokine Receptor Type 2 antibodyAnti-Cxc-R2 antibodyAnti-Cxcr-2 antibodyAnti-Gro/Mgsa Receptor antibodyAnti-High Affinity Interleukin-8 Receptor B antibodyAnti-Il-8r B antibodyAnti-Cd Antigen Cd182 antibodyAnti-Cxcr2 antibodyAnti-Cmkar2 antibodyAnti-Gpcr16 antibodyAnti-Il8rb antibody |
Information sourced from Uniprot.org