Anti-CXCR2/IL-8RB antibody {ABflo® 488} (STJ11109028)

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STJ11109028
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Short Description :Rabbit monoclonal CXCR2/IL-8RB antibody for use in FC in mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:FC
Host:Rabbit
Reactivity:Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Isotype:IgG
Conjugation:ABflo® 488
Purification:Affinity purification
Dilution Range:FC, 5 Mu l per 10^6 cells in 100 Mu l volume
Formulation:PBS with 0.09% Sodium azide, 0.2% BSA, pH7.3.
Storage Instruction:Store at 4°C for up to 1 year from the date of receipt. Do not freeze.
Gene Symbol:Cxcr2
Gene ID:12765
Uniprot ID:CXCR2_MOUSE
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Post Translational Modifications Phosphorylated upon ligand binding.which is required for desensitization.
Function Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Protein Name C-X-C Chemokine Receptor Type 2
Cxc-R2
Cxcr-2
Gro/Mgsa Receptor
High Affinity Interleukin-8 Receptor B
Il-8r B
Cd Antigen Cd182
Database Links Reactome: R-MMU-380108
Reactome: -MMU-418594
Reactome: -MMU-6798695
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-C-X-C Chemokine Receptor Type 2 antibody
Anti-Cxc-R2 antibody
Anti-Cxcr-2 antibody
Anti-Gro/Mgsa Receptor antibody
Anti-High Affinity Interleukin-8 Receptor B antibody
Anti-Il-8r B antibody
Anti-Cd Antigen Cd182 antibody
Anti-Cxcr2 antibody
Anti-Cmkar2 antibody
Anti-Gpcr16 antibody
Anti-Il8rb antibody

Information sourced from Uniprot.org

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