| Short Description : | Rabbit polyclonal CXCR1 (325-339) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CXCR1 |
| Gene ID: | 3577 |
| Uniprot ID: | CXCR1_HUMAN |
| Immunogen Region: | 325-339 |
| Immunogen Sequence: | IFLLCWLPYNLVLLADTLMR TQVIQESCERRNNIGRALDA TEILGFLHSCLNPIIYAFIG QNFRHGFLKILAMHGLVSKE FLARHRVTSYTSSSVNVSSN L |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CXCR1 (NP_000625.1). |
| Function | Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. |
| Protein Name | C-X-C Chemokine Receptor Type 1Cxc-R1Cxcr-1Cdw128aHigh Affinity Interleukin-8 Receptor AIl-8r AIl-8 Receptor Type 1Cd Antigen Cd181 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-C-X-C Chemokine Receptor Type 1 antibodyAnti-Cxc-R1 antibodyAnti-Cxcr-1 antibodyAnti-Cdw128a antibodyAnti-High Affinity Interleukin-8 Receptor A antibodyAnti-Il-8r A antibodyAnti-Il-8 Receptor Type 1 antibodyAnti-Cd Antigen Cd181 antibodyAnti-CXCR1 antibodyAnti-CMKAR1 antibodyAnti-IL8RA antibody |
Information sourced from Uniprot.org
