Anti-CXCL1 antibody (1-107) (STJ28366)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GRO alpha (1-107) antibody for use in WB, IF, ICC and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CXCL1 |
| Gene ID | 2919 |
| Uniprot ID | GROA_HUMAN |
| Immunogen Region | 1-107 |
| Immunogen Sequence | MARAALSAAPSNPRLLRVAL LLLLLVAAGRRAAGASVATE LRCQCLQTLQGIHPKNIQSV NVKSPGPHCAQTEVIATLKN GRKACLNPASPIVKKIIEKM LNSDKSN |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-107 of human GRO alpha (NP_001502.1). |
Additional Info
| Post Translational Modifications | N-terminal processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) are produced by proteolytic cleavage after secretion from peripheral blood monocytes. |
| Function | Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity. |
| Protein Name | Growth-Regulated Alpha ProteinC-X-C Motif Chemokine 1Gro-Alpha(1-73Melanoma Growth Stimulatory ActivityMgsaNeutrophil-Activating Protein 3Nap-3 Cleaved Into - Gro-Alpha(4-73 - Gro-Alpha(5-73 - Gro-Alpha(6-73 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594Reactome: R-HSA-6783783Reactome: R-HSA-6798695 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Growth-Regulated Alpha Protein antibodyAnti-C-X-C Motif Chemokine 1 antibodyAnti-Gro-Alpha(1-73 antibodyAnti-Melanoma Growth Stimulatory Activity antibodyAnti-Mgsa antibodyAnti-Neutrophil-Activating Protein 3 antibodyAnti-Nap-3 Cleaved Into - Gro-Alpha(4-73 - Gro-Alpha(5-73 - Gro-Alpha(6-73 antibodyAnti-CXCL1 antibodyAnti-GRO antibodyAnti-GRO1 antibodyAnti-GROA antibodyAnti-MGSA antibodyAnti-SCYB1 antibody |
Information sourced from Uniprot.org