Anti-CUEDC2 antibody (STJA0008650)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human CUEDC2
General Information
| Short Description | Rabbit polyclonal anti-CUE domain-containing protein 2 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CUEDC2 |
| Gene ID | 79004 |
| Uniprot ID | CUED2_HUMAN |
| Immunogen | Synthesized peptide derived from human CUEDC2 |
| Specificity | This antibody detects endogenous levels of CUEDC2 at Human, Mouse, Rat |
Additional Info
| Function | Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism. |
| Protein Name | Cue Domain-Containing Protein 2 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Cue Domain-Containing Protein 2 antibodyAnti-CUEDC2 antibodyAnti-C10orf66 antibodyAnti-HOYS6 antibody |
Information sourced from Uniprot.org