• Western blot analysis of extracts of various cell lines, using CTSA antibody (STJ27454) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.

Anti-CTSA antibody (210-450) (STJ27454)

SKU:
STJ27454

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CTSA (210-450) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CTSA
Gene ID: 5476
Uniprot ID: PPGB_HUMAN
Immunogen Region: 210-450
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 210-450 of human CTSA (NP_001121167.1).
Immunogen Sequence: SYEQNDNSLVYFAYYHGLLG NRLWSSLQTHCCSQNKCNFY DNKDLECVTNLQEVARIVGN SGLNIYNLYAPCAGGVPSHF RYEKDTVVVQDLGNIFTRLP LKRMWHQALLRSGDKVRMDP PCTNTTAASTYLNNPYVRKA LNIPEQLPQWDMCNFLVNLQ YRRLYRSMNSQYLKLLSSQK YQILLYNGDVDMACNFMGDE WFVDSLNQKMEVQRRPWLVK YGDSGEQIAGFVKEFSHIA
Function Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins.
Protein Name Lysosomal Protective Protein
Carboxypeptidase C
Carboxypeptidase L
Cathepsin A
Protective Protein Cathepsin A
Ppca
Protective Protein For Beta-Galactosidase Cleaved Into - Lysosomal Protective Protein 32 Kda Chain - Lysosomal Protective Protein 20 Kda Chain
Database Links Reactome: R-HSA-1660662
Reactome: R-HSA-2132295
Reactome: R-HSA-4085001
Reactome: R-HSA-4341670
Reactome: R-HSA-6798695
Cellular Localisation Lysosome
Alternative Antibody Names Anti-Lysosomal Protective Protein antibody
Anti-Carboxypeptidase C antibody
Anti-Carboxypeptidase L antibody
Anti-Cathepsin A antibody
Anti-Protective Protein Cathepsin A antibody
Anti-Ppca antibody
Anti-Protective Protein For Beta-Galactosidase Cleaved Into - Lysosomal Protective Protein 32 Kda Chain - Lysosomal Protective Protein 20 Kda Chain antibody
Anti-CTSA antibody
Anti-PPGB antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance