Anti-CTPS1 antibody (402-591) (STJ116216)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CTPS1 (402-591) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CTPS1 |
| Gene ID | 1503 |
| Uniprot ID | PYRG1_HUMAN |
| Immunogen Region | 402-591 |
| Immunogen Sequence | MQLAVVEFSRNVLGWQDANS TEFDPTTSHPVVVDMPEHNP GQMGGTMRLGKRRTLFQTKN SVMRKLYGDADYLEERHRHR FEVNPVWKKCLEEQGLKFVG QDVEGERMEIVELEDHPFFV GVQYHPEFLSRPIKPSPPYF GLLLASVGRLSHYLQKGCRL SPRDTYSDRSGSSSPDSEIT ELKFPSINHD |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 402-591 of human CTPS1 (NP_001896.2). |
Additional Info
| Tissue Specificity | Widely expressed. |
| Function | This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. This enzyme and its product, CTP, play a crucial role in the proliferation of activated lymphocytes and therefore in immunity. |
| Protein Name | Ctp Synthase 1Ctp Synthetase 1Utp--Ammonia Ligase 1 |
| Database Links | Reactome: R-HSA-499943 |
| Cellular Localisation | CytoplasmCytosolMainly Cytosolic But When Active Detected In Long Filamentous StructuresCo-Localizes With Tnk2 In The Cytosolic Filaments |
| Alternative Antibody Names | Anti-Ctp Synthase 1 antibodyAnti-Ctp Synthetase 1 antibodyAnti-Utp--Ammonia Ligase 1 antibodyAnti-CTPS1 antibodyAnti-CTPS antibody |
Information sourced from Uniprot.org