Anti-cTnT antibody [3701] (STJ400209)

SKU:
STJ400209

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Host: Mouse
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-cTnT is suitable for use in ELISA research applications.
Clonality: Monoclonal
Clone ID: 3701
Conjugation: Unconjugated
Isotype: IgG1
Formulation: 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
Purification: Greater than 95% purity
Concentration: 5.0 mg/ml (+/-10 %)
Storage Instruction: Unspecified, storage at 2–8°C. Temperature analysis:-70 °C, 21 days OK-20 °C, 21 days OK +4 °C, 21 days OK +35 °C, 7 days OK +35 °C, 21 days OK +45 °C, 3 days OK +45 °C, 7 days OK. Shelf life stability testing at 2–8 °C in the product buffer.
Determination Method: -
Immunoreactivity: 80–120 % compared to the reference sample in an FIA test
Gene Symbol: TNNT2
Gene ID: 7139
Uniprot ID: TNNT2_HUMAN
Immunogen: Human cardiac troponin T (cTnT)
Tissue Specificity Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart.
Post Translational Modifications Phosphorylation at Thr-213 by PRKCA induces significant reduction in myofilament calcium sensitivity and actomyosin ATPase activity.
Function Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Protein Name Troponin T - Cardiac Muscle
Tntc
Cardiac Muscle Troponin T
Ctnt
Database Links Reactome: R-HSA-390522
Alternative Antibody Names Anti-Troponin T - Cardiac Muscle antibody
Anti-Tntc antibody
Anti-Cardiac Muscle Troponin T antibody
Anti-Ctnt antibody
Anti-TNNT2 antibody

Information sourced from Uniprot.org

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