| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CTNNA3 |
| Gene ID: | 29119 |
| Uniprot ID: | CTNA3_HUMAN |
| Immunogen Region: | 1-240 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human CTNNA3 (NP_001278062.1). |
| Immunogen Sequence: | MKSTQRREKQGSMSAETPIT LNIDPQDLQVQTFTVEKLLE PLIIQVTTLVNCPQNPSSRK KGRSKRASVLLASVEEATWN LLDKGEKIAQEATVLKDELT ASLEEVRKESEALKVSAERF TDDPCFLPKREAVVQAARAL LAAVTRLLILADMIDVMCLL QHVSAFQRTFESLKNVANKS DLQKTYQKLGKELENLDYLA FKRQQDLKSPNQRDEIAGAR ASLKENSPLLHSICSACLE |
| Tissue Specificity | Predominantly expressed in heart and testis. Expressed at lower levels in brain, kidney, liver and skeletal muscle. |
| Function | May be involved in formation of stretch-resistant cell-cell adhesion complexes. |
| Protein Name | Catenin Alpha-3Alpha T-CateninCadherin-Associated Protein |
| Cellular Localisation | CytoplasmCytoskeletonCell JunctionDesmosomeLocalizes To Intercalated Disks Of Cardiomyocytes And In Peritubular Myoid Cells Of TestisAnd Colocalizes With Ctnna1 And Ctnna2Colocalizes With Pkp2 At Intercalated Disks In The Heart |
| Alternative Antibody Names | Anti-Catenin Alpha-3 antibodyAnti-Alpha T-Catenin antibodyAnti-Cadherin-Associated Protein antibodyAnti-CTNNA3 antibody |
Information sourced from Uniprot.org