Anti-CTGF/CCN2 antibody (27-349 aa) [AT18E7] (STJA0041841)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2ak
ImmunogenRecombinant human CTGF (27-349 aa) purified from E. coli
General Information
| Short Description | Mouse monoclonal anti-CTGF/CCN2 (27-349 aa) for use in ELISA, WB, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/ICC/IF |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AT18E7 |
| Isotype | IgG2ak |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-A affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CCN2 |
| Gene ID | 1490 |
| Uniprot ID | CCN2_HUMAN |
| Accession Number | NP_001892 |
| Immunogen | Recombinant human CTGF (27-349 aa) purified from E. coli |
| Immunogen Region | 27-349 aa |
Additional Info
| Tissue Specificity | Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested. |
| Function | Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Is involved in the stimulation of osteoblast differentiation and has a critical role in osteogenesis. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. |
| Protein Name | Ccn Family Member 2Cellular Communication Network Factor 2Connective Tissue Growth FactorHypertrophic Chondrocyte-Specific Protein 24Insulin-Like Growth Factor-Binding Protein 8Ibp-8Igf-Binding Protein 8Igfbp-8 |
| Database Links | Reactome: R-HSA-2032785Reactome: R-HSA-8951671 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Ccn Family Member 2 antibodyAnti-Cellular Communication Network Factor 2 antibodyAnti-Connective Tissue Growth Factor antibodyAnti-Hypertrophic Chondrocyte-Specific Protein 24 antibodyAnti-Insulin-Like Growth Factor-Binding Protein 8 antibodyAnti-Ibp-8 antibodyAnti-Igf-Binding Protein 8 antibodyAnti-Igfbp-8 antibodyAnti-CCN2 antibodyAnti-CTGF antibodyAnti-HCS24 antibodyAnti-IGFBP8 antibody |
Information sourced from Uniprot.org