Anti-CTGF antibody (Internal) (STJ73608)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-CTGF (Internal) is suitable for use in ELISA, Immunofluorescence and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/IF/IHC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Pig/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.IHC: Paraffin embedded Rat Liver. Recommended concentration: 6-8ยตg/ml.IF: Strong expression of the protein seen in the cytoplasm/membrane of NIH3T3 and HepG2 cells. Recommended concen |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | CCN2 |
| Gene ID | 1490 |
| Uniprot ID | CCN2_HUMAN |
| Accession Number | NP_001892.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | TLPVEFKCPDGE |
| Specificity | Immunizing peptide overlaps disulphide bond |
Additional Info
| Function | Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. |
| Protein Name | Ccn Family Member 2Cellular Communication Network Factor 2Connective Tissue Growth FactorHypertrophic Chondrocyte-Specific Protein 24Insulin-Like Growth Factor-Binding Protein 8Ibp-8Igf-Binding Protein 8Igfbp-8 |
| Database Links | Reactome: R-HSA-2032785Reactome: R-HSA-8951671 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Ccn Family Member 2 antibodyAnti-Cellular Communication Network Factor 2 antibodyAnti-Connective Tissue Growth Factor antibodyAnti-Hypertrophic Chondrocyte-Specific Protein 24 antibodyAnti-Insulin-Like Growth Factor-Binding Protein 8 antibodyAnti-Ibp-8 antibodyAnti-Igf-Binding Protein 8 antibodyAnti-Igfbp-8 antibodyAnti-CCN2 antibodyAnti-CTGF antibodyAnti-HCS24 antibodyAnti-IGFBP8 antibody |
Information sourced from Uniprot.org