Anti-CTDSP2 antibody (STJA0008828)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human CTDSP2
General Information
| Short Description | Rabbit polyclonal anti-Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CTDSP2 |
| Gene ID | 10106 |
| Uniprot ID | CTDS2_HUMAN |
| Immunogen | Synthesized peptide derived from human CTDSP2 |
| Specificity | This antibody detects endogenous levels of CTDSP2 at Human, Mouse |
Additional Info
| Function | Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas. |
| Protein Name | Carboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 2Nuclear Lim Interactor-Interacting Factor 2Nli-Interacting Factor 2Protein Os-4Small C-Terminal Domain Phosphatase 2Small Ctd Phosphatase 2Scp2 |
| Database Links | Reactome: R-HSA-381038 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Carboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 2 antibodyAnti-Nuclear Lim Interactor-Interacting Factor 2 antibodyAnti-Nli-Interacting Factor 2 antibodyAnti-Protein Os-4 antibodyAnti-Small C-Terminal Domain Phosphatase 2 antibodyAnti-Small Ctd Phosphatase 2 antibodyAnti-Scp2 antibodyAnti-CTDSP2 antibodyAnti-NIF2 antibodyAnti-OS4 antibodyAnti-SCP2 antibody |
Information sourced from Uniprot.org