| Host: | Goat |
| Applications: | Pep-ELISA/WB/IHC |
| Reactivity: | Human/Mouse/Rat/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-CTDSP1 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 30kDa band observed in Mouse Testis lysates (calculated MW of 29.3kDa according to Mouse NP_694728.1). Recommended concentration: 0.1-0.3µg/ml.IHC: In paraffin embedded Hum |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | CTDSP1 |
| Gene ID: | 58190 |
| Uniprot ID: | CTDS1_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_067021.1; NP_872580.1; NP_001193807.1 |
| Specificity: | This antibody is expected to recognize all three reported isoforms (NP_067021.1; NP_872580.1; NP_001193807.1). |
| Immunogen Sequence: | EAKAQDSDKIC |
| Function | Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. |
| Protein Name | Carboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 1Nuclear Lim Interactor-Interacting Factor 3Nli-IfNli-Interacting Factor 3Small C-Terminal Domain Phosphatase 1Scp1Small Ctd Phosphatase 1 |
| Cellular Localisation | NucleusColocalizes With Rna Polymerase Ii |
| Alternative Antibody Names | Anti-Carboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 1 antibodyAnti-Nuclear Lim Interactor-Interacting Factor 3 antibodyAnti-Nli-If antibodyAnti-Nli-Interacting Factor 3 antibodyAnti-Small C-Terminal Domain Phosphatase 1 antibodyAnti-Scp1 antibodyAnti-Small Ctd Phosphatase 1 antibodyAnti-CTDSP1 antibodyAnti-NIF3 antibodyAnti-NLIIF antibodyAnti-SCP1 antibody |
Information sourced from Uniprot.org
