Anti-CTDSP1 antibody (1-50 aa) (STJ92515)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human CTDSP1 at the amino acid range 1-50
STJ92515
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General Information

Short DescriptionRabbit polyclonal anti-Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (1-50 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IHC/IF/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolCTDSP1
Gene ID58190
Uniprot IDCTDS1_HUMAN
ImmunogenThe antiserum was produced against synthesized peptide derived from the human CTDSP1 at the amino acid range 1-50
Immunogen Region1-50 aa
SpecificityCTDSP1 Polyclonal Antibody detects endogenous levels of CTDSP1 protein.

Additional Info

Function Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
Protein Name Carboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 1
Nuclear Lim Interactor-Interacting Factor 3
Nli-If
Nli-Interacting Factor 3
Small C-Terminal Domain Phosphatase 1
Scp1
Small Ctd Phosphatase 1
Database Links
Cellular Localisation Nucleus
Colocalizes With Rna Polymerase Ii
Alternative Antibody Names Anti-Carboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 1 antibody
Anti-Nuclear Lim Interactor-Interacting Factor 3 antibody
Anti-Nli-If antibody
Anti-Nli-Interacting Factor 3 antibody
Anti-Small C-Terminal Domain Phosphatase 1 antibody
Anti-Scp1 antibody
Anti-Small Ctd Phosphatase 1 antibody
Anti-CTDSP1 antibody
Anti-NIF3 antibody
Anti-NLIIF antibody
Anti-SCP1 antibody

Information sourced from Uniprot.org

Citations

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