Anti-CTDSP1 antibody (Internal) (STJ71150)

SKU:
STJ71150

Current Stock:
Host: Goat
Applications: Pep-ELISA, WB, IHC
Reactivity: Human, Mouse, Rat, Dog
Note: FOR RESEARCH USE ONLY (RUO).
Short Description: Goat polyclonal antibody anti-CTDSP1 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: IHC-5µg/ml
ELISA-antibody detection limit dilution 1:32000.
Storage Instruction: Store at-20 on receipt and minimise freeze-thaw cycles.
Gene Symbol: CTDSP1
Gene ID: 58190
Uniprot ID: CTDS1_HUMAN
Immunogen Region: Internal
Accession Number: NP_067021.1; NP_872580.1
Specificity: This antibody is expected to recognise both reported isoforms (NP_067021.1and NP_872580.1).
Immunogen Sequence: RGKGDQKSAASQK
Function Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
Protein Name Carboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 1
Nuclear Lim Interactor-Interacting Factor 3
Nli-If
Nli-Interacting Factor 3
Small C-Terminal Domain Phosphatase 1
Scp1
Small Ctd Phosphatase 1
Cellular Localisation Nucleus
Colocalizes With Rna Polymerase Ii
Alternative Antibody Names Anti-Carboxy-Terminal Domain Rna Polymerase Ii Polypeptide A Small Phosphatase 1 antibody
Anti-Nuclear Lim Interactor-Interacting Factor 3 antibody
Anti-Nli-If antibody
Anti-Nli-Interacting Factor 3 antibody
Anti-Small C-Terminal Domain Phosphatase 1 antibody
Anti-Scp1 antibody
Anti-Small Ctd Phosphatase 1 antibody
Anti-CTDSP1 antibody
Anti-NIF3 antibody
Anti-NLIIF antibody
Anti-SCP1 antibody

Information sourced from Uniprot.org

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