Anti-CTBP1 antibody [R01-1A2] (STJA0036975)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human CtBP1
General Information
| Short Description | Rabbit monoclonal anti-CTBP1 for use in WB, IHC-P, ICC, IF and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ICC/IF/IP |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R01-1A2 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200IP 1:50 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | CTBP1 |
| Gene ID | 1487 |
| Uniprot ID | CTBP1_HUMAN |
| Immunogen | A synthesized peptide derived from human CtBP1 |
Additional Info
| Tissue Specificity | Expressed in germinal center B-cells. |
| Post Translational Modifications | The level of phosphorylation appears to be regulated during the cell cycle. Phosphorylation by HIPK2 on Ser-422 induces proteasomal degradation. ADP-ribosylated.when cells are exposed to brefeldin A. Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4. |
| Function | Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. |
| Protein Name | C-Terminal-Binding Protein 1Ctbp1 |
| Database Links | Reactome: R-HSA-3769402Reactome: R-HSA-3899300Reactome: R-HSA-4641265Reactome: R-HSA-5339700 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-C-Terminal-Binding Protein 1 antibodyAnti-Ctbp1 antibodyAnti-CTBP1 antibodyAnti-CTBP antibody |
Information sourced from Uniprot.org