Anti-CTBP1 antibody (121-353) (STJ116825)

Name: Anti-CTBP1 antibody (121-353) (STJ116825)
SKU: STJ116825
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ116825

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Short Description	Rabbit polyclonal CTBP1 (121-353) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	CTBP1
Gene ID	1487
Uniprot ID	CTBP1_HUMAN
Immunogen Region	121-353
Immunogen Sequence	PAASVEETADSTLCHILNLY RRATWLHQALREGTRVQSVE QIREVASGAARIRGETLGII GLGRVGQAVALRAKAFGFNV LFYDPYLSDGVERALGLQRV STLQDLLFHSDCVTLHCGLN EHNHHLINDFTVKQMRQGAF LVNTARGGLVDEKALAQALK EGRIRGAALDVHESEPFSFS QGPLKDAPNLICTPHAAWYS EQASIEMREEAAREIRRAIT GRIPDSLKNCVNK
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 121-353 of CtBP1 (NP_001319.1).

Tissue Specificity	Expressed in germinal center B-cells.
Post Translational Modifications	The level of phosphorylation appears to be regulated during the cell cycle. Phosphorylation by HIPK2 on Ser-422 induces proteasomal degradation. ADP-ribosylated.when cells are exposed to brefeldin A. Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4.
Function	Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation.
Protein Name	C-Terminal-Binding Protein 1 Ctbp1
Database Links	Reactome: R-HSA-3769402 Reactome: R-HSA-3899300 Reactome: R-HSA-4641265 Reactome: R-HSA-5339700
Cellular Localisation	Cytoplasm Nucleus
Alternative Antibody Names	Anti-C-Terminal-Binding Protein 1 antibody Anti-Ctbp1 antibody Anti-CTBP1 antibody Anti-CTBP antibody

Information sourced from Uniprot.org