Anti-CT A antibody [R02-1G4] (STJA0034201)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human CT A
General Information
| Short Description | Rabbit monoclonal anti-CT A for use in WB, IHC-F, IHC-P, ICC and IF in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-F/IHC-P/ICC/IF |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R02-1G4 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | PCYT1A |
| Gene ID | 5130 |
| Uniprot ID | PCY1A_HUMAN |
| Immunogen | A synthetic peptide of human CT A |
Additional Info
| Tissue Specificity | Brain, placenta, liver, fetal and adult lung. |
| Post Translational Modifications | The serine residues of the C-terminus are phosphorylated. The inactive soluble form is stabilized by phosphorylation, the active membrane bound form is promoted by anionic lipids or diacylglycerol, and is stabilized by dephosphorylation. Monoubiquitinated by the SCF(FBXL2) complex, leading to proteasomal degradation. |
| Function | Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis. |
| Protein Name | Choline-Phosphate Cytidylyltransferase ACct-AlphaCtp -Phosphocholine Cytidylyltransferase ACct ACt APhosphorylcholine Transferase A |
| Database Links | Reactome: R-HSA-1483191 |
| Cellular Localisation | CytoplasmCytosolMembranePeripheral Membrane ProteinEndoplasmic Reticulum MembraneNucleusIt Can Interconvert Between An Inactive Cytosolic Form And An Active Membrane-Bound Form |
| Alternative Antibody Names | Anti-Choline-Phosphate Cytidylyltransferase A antibodyAnti-Cct-Alpha antibodyAnti-Ctp -Phosphocholine Cytidylyltransferase A antibodyAnti-Cct A antibodyAnti-Ct A antibodyAnti-Phosphorylcholine Transferase A antibodyAnti-PCYT1A antibodyAnti-CTPCT antibodyAnti-PCYT1 antibody |
Information sourced from Uniprot.org