| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CSF3 |
| Gene ID: | 1440 |
| Uniprot ID: | CSF3_HUMAN |
| Immunogen Region: | 30-207 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-207 of human CSF3 (NP_000750.1). |
| Immunogen Sequence: | ATPLGPASSLPQSFLLKCLE QVRKIQGDGAALQEKLVSEC ATYKLCHPEELVLLGHSLGI PWAPLSSCPSQALQLAGCLS QLHSGLFLYQGLLQALEGIS PELGPTLDTLQLDVADFATT IWQQMEELGMAPALQPTQGA MPAFASAFQRRAGGVLVASH LQSFLEVSYRVLRHLAQP |
| Post Translational Modifications | O-glycan consists of Gal-GalNAc disaccharide which can be modified with up to two sialic acid residues (done in recombinantly expressed G-CSF from CHO cells). |
| Function | Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. |
| Protein Name | Granulocyte Colony-Stimulating FactorG-CsfPluripoietinFilgrastimLenograstim |
| Database Links | Reactome: R-HSA-449836Reactome: R-HSA-6783783Reactome: R-HSA-9674555Reactome: R-HSA-9705462 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Granulocyte Colony-Stimulating Factor antibodyAnti-G-Csf antibodyAnti-Pluripoietin antibodyAnti-Filgrastim antibodyAnti-Lenograstim antibodyAnti-CSF3 antibodyAnti-C17orf33 antibodyAnti-GCSF antibody |
Information sourced from Uniprot.org
